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Research of one confocal optical system for ophthalmic applications
S.D. Bazhitov1, A.V. Larichev2, A.V. Razgulin1

1Lomonosov Moscow State University, the Faculty of Computational Mathematics and Cybernetics, Leninskie Gory 1/52, Moscow, 119991, Russia;
2Lomonosov Moscow State University, the Faculty of Physics, Leninskie Gory 1/2, Moscow, 119991, Russia

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DOI: 10.18287/COJ1735

Article ID: 1735

Abstract:
A new mathematical model of a confocal system is developed to solve a problem of optical sectioning of translucent multilayer objects in ophthalmological applications. The model is described by a multidimensional integral equation of the scalar theory of diffraction in the coherent case and allows one to study the dependence of the sectioning quality on the size of the intensity sensor, aberrations of the optical system, and physical parameters of the source.

Keywords:
sectioning, imaging system, confocal system, convolution, blur, aberration.

Citation:
Bazhitov SD, Larichev AV, Razgulin AV. Research of one confocal optical system for ophthalmic applications. Computer Optics 2026; 50(2): 1735. DOI: 10.18287/COJ1735.

References:

  1. Paddok SW, ed. Confocal microscopy methods and protocols. Methods in molecular biology. Humana Press; 1999. ISBN: 978-1-58829-351-0.
  2. Pawley JB, ed. Handbook of biological confocal microscopy. 3rd ed. New York: Springer Science+Business Media LLC; 2006. ISBN: 978-0-387-25921-5.
  3. Jerome WG, Robert LP, eds. Basic confocal microscopy. 2nd ed. Cham, Switzerland: Springer Nature Switzerland AG; 2018. ISBN: 978-3-319-97453-8.
  4. Bille JF, ed. High resolution imaging in microscopy and ophthalmology: New frontiers in biomedical optics. Cham, Switzerland: Springer Nature Switzerland AG; 2019. ISBN: 978-3-030-16637-3.
  5. Wilson T, Sheppard C. Theory and practice of scanning optical microscopy. London: Academic Press; 1984. ISBN: 0-12-757760-2.
  6. Gu M. Principles of three-dimensional imaging in confocal microscopes. Singapore: World Scientific; 1996. ISBN: 978-981-02-2550-6.
  7. Roorda A, Romero-Borja F, Iii DW, Queener H, Hebert T, Campbell M. Adaptive optics scanning laser ophthalmoscopy. Opt Express 2002; 10(9): 405-412. DOI: 10.1364/OE.10.000405.
  8. Williams DR, Burns SA, Miller DT, Roorda A. Evolution of adaptive optics retinal imaging. Biomed Opt Express 2023; 14(3): 1307-1338. DOI: 10.1364/BOE.485371.
  9. Guthoff RF, Baudouin C, Stave J. Atlas of confocal laser scanning in-vivo microscopy in ophthalmology: principles and applications in diagnostic and therapeutic ophthalmology. Berlin, Heidelberg: Springer-Verlag; 2006. ISBN: 978-3-540-32705-9.
  10. Lagali N, ed. Confocal laser microscopy: principles and applications in medicine, biology and the food sciences. InTech; 2013. ISBN: 978-953-51-1056-9.

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